Centrocyte, centroblast and follicular dendritic cell in a follicular lymphoma
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Mikael Häggström, M.D.
Consent note: Consent from the patient or patient's relatives is regarded as redundant, because of absence of identifiable features (List of HIPAA identifiers) in the media and case information (See also HIPAA case reports guidance).
Consent note: Consent from the patient or patient's relatives is regarded as redundant, because of absence of identifiable features (List of HIPAA identifiers) in the media and case information (See also HIPAA case reports guidance).
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Histology of cell types in a germinal center: A centrocyte, a centroblast and a follicular dendritic cell, seen in a follicular lymphoma, H&E stain.
- Centrocytes are small to medium size with angulated, elongated, cleaved, or twisted nuclei.
- Centroblasts are larger cells containing vesicular nuclei with one to three basophilic nucleoli apposing the nuclear membrane.
- Follicular dendritic cells have round nuclei, centrally located nucleoli, bland and dispersed chromatin, and flattening of adjacent nuclear membrane. Reference: Dr. William Kern. Case No.: H-003. Diagnosis: Non-Hodgkin lymphoma, follicular type, low-grade. Organ: Lymph node, inguinal. University of Oklahoma Health Sciences Center, Oklahoma. Last Updated: 12/21/2010
- Centrocytes are small to medium size with angulated, elongated, cleaved, or twisted nuclei.
- Centroblasts are larger cells containing vesicular nuclei with one to three basophilic nucleoli apposing the nuclear membrane.
- Follicular dendritic cells have round nuclei, centrally located nucleoli, bland and dispersed chromatin, and flattening of adjacent nuclear membrane. Reference: Dr. William Kern. Case No.: H-003. Diagnosis: Non-Hodgkin lymphoma, follicular type, low-grade. Organ: Lymph node, inguinal. University of Oklahoma Health Sciences Center, Oklahoma. Last Updated: 12/21/2010
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